Cassia Mizuno

Cassia Mizuno headshot
Pharmaceutical & Admv Sciences
Associate Professor of Medicinal Chemistry
325 Center for Sciences & Pharmacy
Phone: 413-796-2037

Education

Post Doctoral training, USDA-ARS, Oxford, MS
Ph.D, Medicinal Chemistry, University of Mississippi
BS, Pharmacy and Biochemistry, University of Sao Paulo, Brazil

Background

Dr. Cassia Mizuno earned her B.S in Pharmacy and Biochemistry at the University of São Paulo, Brazil. In 2006, she received her Ph.D in Medicinal Chemistry from the University of Mississippi, followed by her postdoctoral training at the USDA-ARS, where she worked on the discovery of natural product-based anticancer agents and environmentally friendly pesticides.

Research Interests

Dr. Mizuno research interests include modification of natural products in the search of compounds with but not limited to anticancer, antimicrobial, anti-parasitic and analgesic activities. Expertise: medicinal chemistry, natural products chemistry, multi-step organic synthesis

Scholarly Works

Journal Articles

Gonçalves, N. S. Mello, T. M. S. P. Mizuno, C. S. Haider, S. Santos, R.A. (2021 ). Cis-trimethoxystilbene, exhibits higher genotoxic and antiproliferative effects than its isomer trans-trimethoxystilbene in MCF-7 and MCF-10A cell lines . Genetics and Molecular Biology ,44 , e20200477.

da Costa, R. M. Bastos, J. K. Costa, M. C. A. Ferreira, M. M. C. Mizuno, C. S. Caramori, G. F. Nagurniak, G. R. Simao, M. R. dos Santos, R. A. Veneziani, R. C. S. Ambrosio, S. R. Parreira, R. L. T (2018 ). In vitro cytotoxicity and structure-activity relationship approaches of ent-kaurenoic acid derivatives against human breast carcinoma cell line. . Phytochemistry ,156

Allen, E. N. Potdar, S. Tapias, V. Parmar, M. Mizuno, C. S. Rimando, A. Cavanaugh, J. E (2018 ). Resveratrol and pinostilbene confer neuroprotection against aging-related deficits through an ERK1/2-dependent mechanism . Journal of Nutritional Biochemistry ,54

Mizuno, C. S. Ampomaah, W. Mendonça, F. M. Andrade, G. C. da Silva, A. M. N. Santos, R.A (2017 ). Cytotoxicity and genotoxicity of stilbene derivatives in CHO-K1 and HepG2 cell lines . Genetic and Molecular Biology. ,40 , 656-664.

Simão, M. R. Carneiro, L.J. dos Santos, R. A. Bastos, J. K. Veneziani, R. C. S. Ambrósio, S. R. Mizuno, C. S. (2016 ). In vitro cytotoxicity study of ent-kaurenoic acid derivatives against human breast carcinoma cell line. . Medicinal Chemistry Research ,25

Mizuno, C. S. Souza, A. B. Tekwani, B. L. Ambrósio, S. R. Veneziani, R. C.S. (2015 ). Synthesis and biological evaluation of polyalthic acid derivatives for the treatment of neglected diseases. Bioorganic and Medicinal Chemistry letters. . Bioorganic and Medicinal Chemistry letters ,25 , 5529-553..