Mohammadhossein Gilzad Kohan

Education

PhD in Pharmaceutical Sciences, University of Alberta, Edmonton, Canada
Doctor of Pharmacy (PharmD), University of Tehran, Iran

Interests

Dr. Gilzad Kohan’s interests include developing clinical and non-clinical PK/PD projects, which investigate pathophysiological changes in the action and disposition of the drugs. In addition, he is interested in chemical structure modification (including pro-drug synthesis) in order to improve pharmacokinetic (PK) properties of anti-cancer and anti-inflammatory drugs. Additionally, his research involves drug-disease interaction studies and nano-medicine design.

Scholarly Works

Journal Articles

Alfonso Ramirez, Kathleen A. Bielecki-Wilken, David Baker, Shabnam Sani, Hamed Gilzad- Kohan (2021 , April ). In vitro permeability, irritability, and release evaluation of commonly used topical diclofenac gel preparations (1, 5, and 10 ) . Int J Pharm Compounding

Gilzad-Kohan H, Jamali F (2021 ). Anti-Inflammatory Properties of Drugs Used to Control COVID-19 and their Effects on the Renin-Angiotensin System and Angiotensin-Converting Enzyme-2 . J Pharm Pharm Sci

4. Bakhteyar Hamid, Cassone Clayton, Hamed Gilzad-Kohan, Sani Shabnam N (2017 , September ). Kinetic Analysis of Drug Release from Compounded Slow-Release Capsules of Liothyronine Sodium (T3) . Int J Pharm Compounding

Gilzad-Kohan H, Sani S, Boroujerdi M. (2017 , June ). Calcitriol Reverses Induced Expression of Efflux Proteins and Potentiates Cytotoxic Activity of Gemcitabine in Capan-2 Pancreatic Cancer Cells . J Pharm Pharm Sci

Vandhana Muralidharan-Chari, Hamed Gilzad-Kohan, Alex Asimakopoulos, Thangirala Sudha, Stewart Sell, Kannan Kurunthachalam, Mehdi Boroujerdi, Shaker A Mousa (2015 ). Removal of Therapeutic Drugs by Microvesicles Contributes to Drug Resistance in Cancer Cells .

Gilzad-Kohan, M.H Boroujerdi, M (2015 ). Time Course and dose dependency of Influx and Efflux Protein Expression after Treatment with Gemcitabine in Pancreatic Cancer Cells . Xenobiotica , 1-11.

Gilzad-Kohan, M.H. Kaur, K. Jamali, F (2015 ). A Novel Peptide Pro-drug of Glucosamine with Enhanced Gut Permeability . PLoS One

Gilzad-Kohan, M. H. K. Kaur and Jamali, F. (2013 ). The Antiinflammatory Action and Pharmacokinetics of a Novel Di-Peptide Aminosugar . J Pharm Pharm Sci ,16 , 279-288.

Agahzadeh-Habashi, A. Gilzad-Kohan, M. Jamali, F. (2013 ). Glucosamine Dose-Effect Correlation in Adjuvant Arthritis Rat . Journal of Osteoarthritis Cartilage

Gilzad-Kohan, M. H. Jamali, F. (2012 ). Glucosamine and adjuvant arthritis: a pharmacokinetic and pharmacodynamic study . Eur. J. Pharm. Sci. ,47 , 387-393.

Ibrahim, A. Gilzad-Kohan, M. H. Aghazadeh-Habashi, A. Jamali, F. (2012 ). Absorption and bioavailability of glucosamine in the rat . J. Pharm. Sci. ,101 , 2574-2583.

M. H. D. Kamal Al-Hallak, Muhammad Khan Sarfraz, Shirzad Azarmi, M. H. Gilzad Kohan, Wilson H. Roa, and Raimar Löbenberg (2011 , March ). Microcalorimetric Method to Assess Phagocytosis: Macrophage-Nanoparticle Interactions . AAPS J. ,13 , 20-29.

Courses Taught

PHAR 514 Pharmaceutics I

PHAR 515 Pharmaceutics I Lab

PHAR 610 Principles of Pharmacokinetics

PHAR 525 Pharmaceutics lab

PHAR 656 Drug Discovery & Development

PHAR 690 Cosmeceuticals